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Autohemotherapy and Inflammatory Bowel Disease (IBD)

IBD is an isolating, frustrating, exhausting, unpredictable, overwhelming, debilitating, annoying, and stressful disease. At present, there is no cure for IBD, and is considered an ongoing and life-long disease. Will the practice of Autohemotherapy (AHT) change all this?

Inflammatory bowel disease (IBD) is a term for two conditions, Crohn’s Disease and Ulcerative Colitis that are characterized by chronic inflammation of the gastrointestinal (GI) tract. Prolonged inflammation results in damage to the GI tract leading to the disruption of natural processes such as the digesting of food, the absorption of nutrients and the elimination of waste products. Some people have periods of good health (remission) as well as times when symptoms are more active (relapses or flare-ups). Everyone is different: in many people the disease runs a benign course with few flare-ups, while other people may have more severe disease.

It's estimated that 1 in 5 people with ulcerative colitis have severe symptoms that do not improve with medicine. In these cases, surgery may be necessary to remove an inflamed section of large bowel (colon). Around 60 to 75% of people with Crohn's disease will need surgery to repair damage to their digestive system and treat complications of Crohn's disease. People with ulcerative colitis or Crohn's disease are also at increased risk of getting bowel cancer.

At present, treatment for IBD involves:

1. Surgery - 23 to 45 percent of people with ulcerative colitis and up to 75 percent of people with Crohn's disease will eventually require surgery. Some people with these conditions have the option to choose surgery, while for others, surgery is an absolute necessity due to complications of their disease.

2. Drugs

a) Immunosuppressants

b) Anti-inflammatory drugs

c) Other types of drugs – eg. Anti-diarrheals, pain relievers, iron supplements, Vit B12, calcium & Vit D supplements

Many of the immunosuppressant drugs have horrendous negative side effects. The list is extensive, everything from mild negative effects such as headache, fever, itchy skin to infections to cancer. Eg. Azasan -negative side effects include: a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. This has occurred mainly in teenagers and young men with Crohn's disease or ulcerative colitis; This medicine can harm an unborn baby; Azasan weakens your body's immune system; Common (1% to 10%): Cervical cancer, Kaposi's sarcoma, non-Hodgkin's lymphoma, squamous cell carcinoma of the skin, vulval cancer (renal homograft patients); The majority of reported cases of hepatosplenic T-cell lymphoma have bee in patients with Crohn's disease or ulcerative colitis, and were adolescent and young adult males.

Anti-inflammatory drugs, eg. Aminosalicylates- eg. Azulfidine, Asacol HD, Delzicol -some of the negative side effects are: anorexia, headache, nausea, vomiting, gastric distress, and reversible oligospermia, skin rash, pruritus, urticaria, fever, Hemolytic anemia, aplastic anemia, agranulocytosis, leukopenia, megaloblastic (macrocytic) anemia, purpura, thrombocytopenia, hypoprothrombinemia, methemoglobinemia, congenital neutropenia, and myelodysplastic syndrome, erythema multiforme (Stevens-Johnson syndrome), exfoliative dermatitis, epidermal necrolysis (Lyell's syndrome) with corneal damage, Guillian-Barre syndrome, peripheral neuropathy, mental depression, vertigo, hearing loss, insomnia, ataxia, hallucinations, tinnitus, and drowsiness, nephrosis with oliguria and anuria, nephritis, nephrotic syndrome, urinary tract infections, hematuria, crystalluria, proteinuria, and hemolytic-uremic syndrome.

3. Nutritional Therapy - Proper Diet - Your doctor may recommend a special diet given via a feeding tube (enteral nutrition) or nutrients injected into a vein (parenteral nutrition) to treat your Crohn's disease.

Your doctor may also recommend a low residue or low-fiber diet to reduce the risk of intestinal blockage if you have a narrowed bowel (stricture). A low residue diet is designed to reduce the size and number of your stools.

The exact cause of IBD is unknown, but IBD is the result of a defective immune system and affects millions of people worldwide. A properly functioning immune system attacks foreign organisms, such as viruses and bacteria, to protect the body. In IBD, the immune system responds incorrectly to environmental triggers, which causes inflammation of the gastrointestinal tract.

The mononuclear phagocytic system (MPS) is a part of the immune system that consists of phagocytic cells located just about everywhere in the body, the skin, lungs, intestine, brain, central nervous system, lymph nodes, spleen, bone marrow, blood, etc.

Élie Metchnikoff, who won the Nobel Prize 100 years ago for his description of phagocytosis, proposed that the key to immunity was to “stimulate the phagocytes”.

In Inflammatory Bowel Disease there is an imbalance of certain types of macrophages in the lining of the gastrointestinal tract. Macrophages are large phagocytic cells which are found in essentially all tissues, where they patrol for potential pathogens. Macrophages originate from the white blood cells known as monocytes which are produced by the bone marrow. Monocytes leave the blood circulation and enter the tissues where they differentiate into macrophages. They are a part of our immune system and are characterized by plasticity and versatility.

Basically, there are 2 types of macrophages. Macrophages that encourage inflammation are called M1 macrophages, whereas those that decrease inflammation and encourage tissue repair are called M2 macrophages.

In inflammatory diseases, like Crohn's, macrophages mediate the inflammatory destruction of the gut. Just how the tissue reacts (inflammation or suppression) is dependent on the type of macrophage cell present, and how it is stimulated. The imbalance of the macrophage types is related to a number of immunity-related diseases. For example, it has been shown that increased M1/M2 ratio correlates with development of inflammatory bowel disease, an immunodeficiency state, a lack of M2 macrophages.

AHT (without the use of ozone) stimulates your immune system (it does not overstimulate it) to produce monocytes from the bone marrow which help to replenish and maintain appropriately sized tissue-resident macrophage pools in the intestine (and elsewhere in the body). Due to their plasticity and versatility, these newly residential tissue macrophages will adapt to their local environment and perform their specific functions as either M1 or M2 macrophages depending what is required. This causes a reset by essentially balancing out the types of macrophages in the gastrointestinal tract (and elsewhere in the body) required for tissue homeostasis and immunity.

You did not always have IBD. Something happened along the way to cause an imbalance of these immune cells in your intestine. Now they want you to take drugs that actually suppress your immune system so that you cannot replenish and balance out the type of immune cells required to maintain proper immunity and health. It is not a suppression of the immune system that you want. What you want is something that will correct it, reset it, balance it out and that is exactly what AHT does.

Unfortunately, we will probably never see clinical trials done on AHT due to the fact that most are funded by the pharmaceutical companies and I don’t see them funding something that will put them out of business. Also, I hate to say it, but many physicians are so imbedded in the big pharma model of education and the big pharma model of what the solution is. That solution is typically a direct line from the disease, typically a virus or bug and then recommending a vaccine or some harsh chemical solution and most of this has to do with profiting the very big pharma companies. It will be up to us as individuals to move this therapy to the forefront and hopefully change the paradigm of medicine.

AHT is inexpensive, it can be done anywhere and anytime. You are in control and it will always be available to you. No one can own the patent on this and control its’ availability. This is a therapy that has been used successfully in treating people for over a hundred years. It may be a little more invasive than swallowing a pill, but there have been no recorded negative side effects, only positive ones.

After 10 yrs. I personally have had no negative side effects other than bruising or hitting a nerve once in awhile. I have experienced numerous positive side effects as have many other people I know that are practicing AHT. I have witnessed the healing properties of AHT in regards to Chron’s Disease, acne, psoriasis, arthritis, viral and bacterial infections, increased healing time of injuries and wounds, urticaria, relief from allergies and asthma, helps with depression, anxiety and stress just to list a few. We have only scratched the surface with what AHT is capable of doing. With an optimally running immune system, a lot of disease will disappear. You have nothing to lose by trying AHT and everything to gain. This therapy will benefit every body.


Dale Lane

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